Cayce Shaw
Assistant Professor
Full-Time Faculty
Harney Science Center 370
Biography
Cayce Shaw received her BS from the University of California, Santa Cruz, where she majored in Biochemistry and Molecular Biology and was a four-year starter on the NCAA women's soccer team. She then completed her Ph.D. at University of California, San Francisco where her thesis investigated the biochemical and enzymatic mechanisms of Kdm6a, a lysine demethylase (H3K27me2/3) known to escape X chromosome inactivation in the brain.
Expertise
- Chemistry
- Biochemistry
Research Areas
- Biochemistry
- X-chromosome Biology
Education
- UC San Francisco, PhD in Rehabilitation Science, Neuroscience Emphasis, 2024
- UC Santa Cruz, BS (cum laude) in Biochemistry and Molecular Biology, 2019
Selected Publications
- Gadek M., Shaw C. K., Abdulai-Saiku S., Saloner R., Marino F., Wang D., Bonham L. W., Yokoyama J. S., Panning B., Benayoun B. A., Casaletto K. B., Ramani V., Dubal D. B. Aging activates escape of the silent X chromosome in the female mouse hippocampus. Sci Adv. 2025 Mar 7;11(10):eads8169.
- Shaw C. K., Abdulai-Saiku S., Marino F., Wang D., Davis E. J., Panning B., Dubal D. B. X chromosome factor Kdm6a enhances cognition independent of its demethylase function in the aging XY male brain. J Gerontol A Biol Sci Med Sci. 2023 Jan 9:glad007.
- Arnold, A.P., Abdulai-Saiku, S., Chesselet, M.F., Dubal, D.B., Shaw, C. K., Gold, S., McCullough, L., Werling, D. (2022). Sex Differences and Neurological Disease chapter. In Zigmond, M.J., Wiley, C.A., Chesselet, M.F. Neurobiology of Diseases, 2nd Edition. Elsevier.