Osasere Evbuomwan

Osasere Evbuomwan

Assistant Professor

Full-Time Faculty

(415) 422-4914 Harney Science Center, 370

Biography

Professor Evbuomwan received her BS in Chemistry with a minor in Mathematics from Lewis-Clark State College in Lewiston, Idaho in May 2006. Later that year, she joined the chemistry program at the University of Texas at Dallas where she received her PhD in Chemistry under the supervision of A. Dean Sherry. Evbuomwan spent an additional year at UT Dallas as a postdoctoral research associate after which she was selected as one of ten Madrid-MIT M+Vision Postdoctoral Research Fellows at MIT. In 2015, she began a tenure-track faculty position at Gonzaga University where she taught a variety of upper and lower division courses in Chemistry and performed research with undergraduates in the field of Biomedical Imaging.

At USF, Evbuomwan’s research endeavors are primarily focused on the development of Magnetic Resonance Imaging (MRI) and Optical Imaging agents for prostate cancer diagnosis, and image-guided tumor resection. All projects span inorganic chemistry, organic chemistry, analytical chemistry, and biomedical imaging, and introduce students to the interdisciplinary nature of research. In addition to synthesizing multi-dentate ligands and their corresponding lanthanide complexes, students will become familiar with common analytical techniques such as NMR, HPLC, MS, Luminescence, and UV-Vis Spectrophotometry.

Appointments
Assistant Professor, Gonzaga University (2015 – 2018)
Education
PhD, University of Texas at Dallas
Postdoctoral Research Associate, University of Texas at Dallas
Postdoctoral Fellow, Massachusetts Institute of Technology (MIT)
Selected Publications

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Zhang, L., Evbuomwan, O. M., Tieu, M., Zhao, P., Martins, A. F., and Sherry, A. D., Protonation of carboxyl groups in EuDOTA-tetraamide complexes results in catalytic prototropic exchange and quenching of the CEST signal, in Philosophical Transactions of the Royal Society A, 2017, 375: 20170113, 1 – 8.

Evbuomwan, O. M., Terreno, E., Aime, S., Sherry, A. D., Chapter 10: CEST and PARACEST agents for molecular imaging, in “The Chemistry of Molecular Imaging” by Nicholas Long, Wing-Tak Wong, and Edmund H. Immergut, Wiley Interscience, 2014. ISBN-13: 9781118093276.

Evbuomwan, O. M. Lee, J. Woods, M. Sherry, A.D. The presence of fast exchanging proton species in aqueous solutions of paraCEST agents can impact rate constants measured for slower exchanging species when fitting CEST spectra to the Bloch equations, in Inorganic Chemistry, 2014, 53(16), 10012 – 10014.

Mani, T., Opina, A., Zhao, P., Evbuomwan, O. M., Milburn, N., Tircso, G., Kumas, C., and Sherry, A. D., The stereochemistry of amide side chains containing carboxyl groups influences water exchange rates in EuDOTA-tetraamide complexes, in Journal of Biological Inorganic Chemistry 2013, 19(2), 161 – 171.

Evbuomwan, O. M., Kiefer, G., and Sherry, A. D., Amphiphilic EuDOTA-tetraamide complexes form micelles with enhanced CEST sensitivity, Eur. J. Inorg. Chem. 2012, (12), 2126 – 2134.

Evbuomwan, O. M., Merritt, M., Kiefer, G., and Sherry, A.D., Nanoparticle-based PARACEST agents: The quenching effect of amine-functionalized silica nanoparticles on the CEST signal from surface conjugated chelates, Contrast Media & Molecular Imaging 2012, 7(1), 19 – 25.

Wu, Y., Evbuomwan, M., Melendez, M., Opina, A., and Sherry, A. D., Advantages of macromolecular to nanosized chemical-exchange saturation transfer agents for MRI applications, in Future Medicinal Chemistry 2010, 2(3), 351 – 366.