Juliet  Spencer

Juliet Spencer


Juliet Spencer joined the faculty in 2003 after spending several years as a drug discovery scientist in the biotechnology industry. She has an active research laboratory that investigates herpes viruses and the way they manipulate host immune responses. She has been recognized with the Arthur Furst Award for outstanding research and the Ellen Weaver Award for mentoring women in science. In 2013 she established the Fletcher Jones Microscopy Center, bringing advanced imaging technology to USF. In 2014, she was named the Deans Scholar for the Sciences, and in 2015 she received the Distinguished Research Award.  She is dedicated to training the next generation of scientists and tries to infect every student with her contagious enthusiasm for the life sciences.

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Ph.D. Microbiology, University of Virginia
B.S. Biotechnology, Worcester Polytechnic Institute

Research Areas

Virus-Host Interactions
The Avon Breast Cancer Study at USF

Courses Offered
  • General Microbiology
  • Medical Microbiology
  • First Year Seminar: Good Germs, Bad Germs

Christiaansen, A., Varga, S.M., and J.V. Spencer.  2015.  Viral manipulation of the host immune response.  Curr Opin Immun 2015, 36:54–60.

Bishop R.K., Valle Oseguera C.A.,  and J.V. Spencer.  2015.  Human Cytomegalovirus interleukin-10 promotes proliferation and migration of MCF-7 breast cancer cells.  Cancer Cell Microenviron. 2(1):e678.

Tu, C.C. and J.V. Spencer. 2014. The DRY Box and C-Terminal Domain of the Human Cytomegalovirus US27 Gene Product Play a Role in Promoting Cell Growth and Survival. PLoS One. 9(11):e113427.

Arnolds, K.L. and J.V. Spencer. 2014. CXCR4: a virus's best friend? Infect Genet Evol 25:146-56. 

Valle Oseguera C.A. and J.V. Spencer. 2014. cmvIL-10 Stimulates the Invasive Potential of MDA-MB-231 Breast Cancer Cells. PLoS ONE 9(2): e88708.

Lares, A.P., Tu, C.C., and J.V. Spencer. 2013. The Human Cytomegalovirus US27 gene product enhances cell proliferation and alters cellular gene expression. Virus Res 176: 312-320.

Arnolds, K.L., Lares, A.P., and J.V. Spencer. 2013. The US27 gene product of human cytomegalovirus enhances signaling of host chemokine receptor CXCR4. Virology 439: 122-131.

Stapleton, L.K., Lares, A.P., Arnolds, K.L., Devito, T.M., and J.V. Spencer. 2012. Receptor chimeras demonstrate that the C-terminal domain of the human cytomegalovirus US27 gene product is necessary and sufficient for intracellular receptor localization. Virol J 9:42.

Brodeur, N.D. and J.V. Spencer. 2010. Antibodies to human IL-10 neutralize ebvIL-10-mediated cytokine suppression but have no effect on cmvIL-10 activity. Virus Res 153:265-8

Slobedman, B., P.A. Barry, J. V. Spencer, S. Avdic, and A. Abendroth. 2009. Virus-encoded homologs of cellular interleukin-10 and their control of host immune function. J Virol 83:9618-9629