Chemistry — Environmental Management — Environmental Science
William  Karney

William Karney


Ph.D., University of California, Los Angeles

William Karney received his Ph.D. in Organic Chemistry from the University of California, Los Angeles, in 1994. Prior to his position at USF he did postdoctoral work at the University of Washington and the University of California, Berkeley.

At USF, William teaches undergraduate and graduate courses in environmental chemistry, air pollution, water treatment, and instrumental analysis. His research, performed in collaboration with Professor Claire Castro (Chemistry), involves the use of computational chemistry to understand the structures, energetics, and properties of organic compounds and the mechanisms of organic reactions. Recent projects include the elucidation of mechanisms for dynamic processes in annulenes and the high-temperature rearrangements of polycyclic aromatic hydrocarbons (PAHs). His work is funded by the National Science Foundation.

Selected Publications:

Brayfindley, E.; Irace, E. E.; Castro, C.; Karney, W. L.  J. Org. Chem.  2015, 80, in press.  DOI: 10.1021/acs.joc.5b00066. "Stone–Wales Rearrangements in Polycyclic Aromatic Hydrocarbons: A Computational Study."

Santander, M. V.; Pastor, M. B.; Nelson, J. N.; Castro, C.; Karney, W. L., J. Org. Chem.2013, 78, 2033-2039. DOI: 10.1021/jo302072p. "Hückel and Möbius Bond-shifting Routes to Configuration Change in Dehydro[4n+2]annulenes."

Pastor, M.B.; Kuhn, A.J.; Nguyen, P.T.; Santander, M.V.; Castro, C.; Karney, W.L.,J. Phys. Org. Chem2013, 26, 750-754.  DOI:  10.1002/poc.3126. "Hydrogen Shifts and Benzene Ring Contractions in Phenylenes."

Castro, C.; Karney, W. L., J. Phys. Org. Chem.2012,25, 612-619. "Mechanisms and Möbius Strips: Understanding Dynamic Processes in Annulenes."

Januar, L. A.; Huynh, V.; Wood, T. S.; Castro, C.; Karney, W. L., J. Org. Chem.2011, 76, 403-407. "Dehydro[12]annulenes: Structures, Energetics, and Dynamic Processes."

Okoronkwo, T.; Nguyen, P. T.; Castro, C.; Karney, W. L., Org. Lett.2010, 12, 972-975. "[14]Annulene: Cis/trans Isomerization via Two-twist and Nondegenerate Planar Bond Shifting, and Möbius Conformational Minima."

Dosa, P. I.; Gu, Z.; Hager, D.; Karney, W. L.; Vollhardt, K. P. C., Chem. Commun.2009, 1967-1969. "Flash-Vacuum-Pyrolytic Reorganization of Angular [4]Phenylene."

Castro, C.; Karney, W. L.; Noey, E.; Vollhardt, K. P. C., Org. Lett.2008, 10, 1287-1290. "Competing Isomerizations of [12]Annulenes: Diels-Alder Reaction versus Electrocyclization."

Moll, J. F.; Pemberton, R. P.; Gutierrez, M. G.; Castro, C.; Karney, W. L., J. Am. Chem. Soc.2007, 129, 274-275. "Configuration Change in [14]Annulene Requires Möbius Antiaromatic Bond Shifting."

Castro, C.; Karney, W. L.; Valencia, M. A.; Vu, C. M. H.; Pemberton, R. P., J. Am. Chem. Soc.2005, 127, 9704-9705. "Möbius Aromaticity in [12]Annulene: Cis-Trans Isomerization via Twist-Coupled Bond Shifting."

Castro, C.; Isborn, C. M.; Karney, W. L.; Mauksch, M.; Schleyer, P. v. R., Org. Lett.2002, 4, 3431-3434. "Aromaticity with a Twist: Möbius [4n]Annulenes."

Karney, W. L.; Borden, W. T., J. Am. Chem. Soc.1997, 119, 1378-1387. "Ab Initio Study of the Ring Expansion of Phenylnitrene and Comparison with the Ring Expansion of Phenylcarbene."



Ph.D., University of California, Los Angeles

Research Areas

Physical organic chemistry
Hydrocarbon reaction mechanisms